Biochemistry & Cell Biology (BIOC)

BIOC 112 - INTRODUCTORY BIOLOGICAL RESEARCH CHALLENGES

Short Title: INTRO BIOL RESEARCH CHALLENGES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hour: 1

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Lower-Level

Description: Teams of students work on investigative, client-based projects with opportunities to design experiments, analyze data, and communicate their findings. This course is recommended for students interested in the Biosciences major who have very limited practical laboratory experience. Only first year students may enroll. Mutually Exclusive: Credit cannot be earned for BIOC 112 and BIOC 111/NSCI 120.

BIOC 115 - FRESHMAN SEMINAR IN LOCAL BIOLOGY RESEARCH (BCB)

Short Title: FRESHMAN BIOLOGY SEMINAR (BCB)

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Distribution Group: Distribution Group III

Credit Hour: 1

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Lower-Level

Description: A 7-week seminar course to introduce freshmen prospective biologists to the excitement of research at Rice and the Medical Center and to provide context with which to think about facts presented in biosciences textbooks. Small groups will meet weekly with a graduate student or postdoctoral researcher to explore a published research article by a local lab, gaining background information about the subject and exposure to the research techniques. In the final session, the group will tour the lab that produced the featured article. Additional tours and activities TBA. All first-year non-transfer students are eligible to enroll in BIOC 115/FSEM 115 regardless of AP credit. This course meets in the second half of the semester and features research in the Program of Biochemistry and Cell Biology. Cross-list: FSEM 115.

Course URL: www.bioc.rice.edu/bioc115/

BIOC 122 - CURRENT TOPICS IN BIOLOGY

Short Title: BIOLOGY FOR VOTERS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Restrictions: Students cannot enroll who have a major in Biochemistry and Cell Biology, Biological Sciences or Ecology & Evolutionary Biology. Graduate level students may not enroll.

Course Level: Undergraduate Lower-Level

Description: Designer babies, climate change, the anti-vaccine movement, gender identity, evolution…exploring these and other socially relevant topics will provide a context for learning essential concepts in biology and ways to distinguish science truth from science fiction.

Course URL: www.ruf.rice.edu/~bioslabs/bioc122/

BIOC 129 - BRAINSTEM - TEACHING STEM THROUGH NEUROSCIENCE

Short Title: BRAINSTEM

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Internship/Practicum

Credit Hour: 1

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Lower-Level

Description: BrainSTEM is a service organization that teaches STEM subjects through the lens of neuroscience. We perform hands-on, small-group activities with ~45 students per week. This course will prepare you to communicate science in a both effective and entertaining manner, as well as build your skills in managing small groups. More information can be found at ‘www.brainstem.club.’ Repeatable for Credit.

BIOC 201 - INTRODUCTORY BIOLOGY

Short Title: INTRODUCTORY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Lower-Level

Description: Chemistry and energetics, cell physiology, cell biology, Mendelian genetics, molecular genetics, developmental biology, and plant physiology.

BIOC 205 - MICROBE HUNTERS REVISITED

Short Title: MICROBE HUNTERS REVISITED

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 2

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Lower-Level

Description: This seminar will review important microbiologists and their discoveries of infectious agents. From Pasteur to Prusiner, we will review the infectious agents they described, as well as the methods used for their discovery. The classic text by Paul de Kruif entitled "Microbe Hunters" will be the basis for half of the course material.

BIOC 211 - INTERMEDIATE EXPERIMENTAL BIOSCIENCES

Short Title: EXPERIMENTAL BIOSCIENCES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hours: 2

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Lower-Level

Prerequisite(s): BIOC 201 (may be taken concurrently) and

Description: Introduction to scientific method, principles of experimental design, selected research strategies, record keeping, and technical communication as related to biological science. The prereq BIOC 201 may be taken concurrently with BIOC 211. Mutually Exclusive: Credit cannot be earned for BIOC 211 and BIOC 212.

BIOC 212 - INTERMEDIATE EXPERIMENTAL CELLULAR AND MOLECULAR NEUROSCIENCE

Short Title: EXPERIMENTAL NEUROSCIENCE

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 2

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Lower-Level

Prerequisite(s): BIOC 201 (may be taken concurrently) and

Description: Introduction to the scientific method, principles of experimental design, selected research strategies, record keeping, and technical communication as related to neuroscience. This course is primarily intended for prospective and declared NEUR majors. The pre-req BIOC 201 may be taken concurrently with BIOC 212. Instructor Permission Required. Mutually Exclusive: Credit cannot be earned for BIOC 212 and BIOC 211.

BIOC 215 - BIOSCIENCES LAB TEACHING

Short Title: BIOC LAB TEACHING

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1-3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Lower-Level

Description: Undergraduate teaching in a biosciences laboratory. Provide group and individual instruction and feedback to undergraduates during and outside of laboratory classes. Instructor Permission Required. Repeatable for Credit.

BIOC 216 - DISCUSSION SECTION TEACHING

Short Title: DISCUSSION SECTION TEACHING

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Independent Study

Credit Hour: 1

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Lower-Level

Description: In this course, undergraduates who have previously excelled in a BIOC course, as approved by the Department Chair for this activity, will develop teaching skills by leading discussion sections or serving as writing mentors. These activities are designed to benefit students presently taking the relevant BIOC course and will be performed under the guidance of the professor teaching the course. Instructor Permission Required. Repeatable for Credit.

BIOC 220 - FORENSIC BIOLOGY AND CRIMINALISTICS

Short Title: FORENSIC BIOL & CRIMINALISTICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Lower-Level

Prerequisite(s): BIOC 201

Description: This course will introduce students to certain areas of forensic science including - crime scene analysis, forensic serology, molecular genetics (DNA), forensic toxicology; drugs, and the identification of biological fluids such as blood, saliva, and semen, with case studies and a potential field trip. The course is designed for biology and chemistry students, for students interested in the application of biosciences in DNA and crime scene analysis.

BIOC 300 - PARADIGMS IN BIOCHEMISTRY AND CELL BIOLOGY

Short Title: PARADIGMS IN BIOCHM & CELL BIO

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Description: Examination of paradigms in Biochemistry and Cell Biology with a focus on the "central dogma" of molecular biology. Recommended strongly for students with Advanced Placement in Biology and designed for prospective BIOC majors. This course is strongly recommended as preparation for BIOC 341 (Cell Biology). Enrollment is restricted to students who have not yet taken BIOC 301 or BIOC 341. Recommended Prerequisite(s): Recommended strongly for students with Advanced Placement in Biology and designed for prospective BIOC majors. For students with AP credit for BIOS/BIOC 201, this course is strongly recommended as preparation for BIOC 341 (Cell Biology).

BIOC 301 - BIOCHEMISTRY I

Short Title: BIOCHEMISTRY I

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): CHEM 211 and BIOC 201

Description: The second in an integrated sequence of three courses (BIOC 201, 301, 302). Structure and function of proteins, enzymes, and nucleic acids; enzyme kinetics; glycolysis, aerobic metabolism, and energy coupling. Recommended Prerequisite(s): CHEM 212.

BIOC 302 - BIOCHEMISTRY II

Short Title: BIOCHEMISTRY II

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 301

Description: The final in an integrated sequence of three courses (BIOC 201, 301, 302). In depth study of carbohydrate, amino acid, and lipid metabolic pathways, hormone regulation of metabolic path ways, key cell signaling mechanisms, and the structural biology of DNA replication, transcription, and translation into proteins. Course also involves analysis of primary scientific literature. Recommended Prerequisite(s): CHEM 212 or CHEM 320.

BIOC 305 - INVESTIGATIVE BIOCHEMISTRY

Short Title: INVESTIGATIVE BIOCHEMISTRY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hours: 2

Restrictions: Enrollment limited to students with a class of Junior or Senior. Students cannot enroll who have a major in Biochemistry and Cell Biology, Biological Sciences or Ecology & Evolutionary Biology. Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 301 (may be taken concurrently)

Description: In this course designed for premedical students not majoring in the Biosciences, students work in teams to complete part of a research project. In addition to gaining practical laboratory experience in biochemistry, students maintain a laboratory notebook, generate and analyze data, and write a research paper. The prerequisite BIOC 301 may be taken concurrently with BIOC 305.

BIOC 310 - INDEPENDENT RESEARCH FOR BIOCHEMISTRY AND CELL BIOLOGY UNDERGRADUATES

Short Title: IND RES FOR BIOC UNDERGRADS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Research

Credit Hours: 1-4

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 111 or BIOC 211 or BIOC 112 or NSCI 120

Description: Independent research in Rice BCB faculty laboratories (sections 2 and above) or other Texas Medical Center laboratories (sections 1). Students spend at least 3 hours per week in the laboratory for each semester hour of credit. If taken for 3 or more hours, counts as one required 300+ level lab course (not BIOC 311). Requires a proposal abstract, weekly reports, and a research paper (fall semester) or a proposal abstract, weekly reports, and a poster presentation (spring semester). Students wishing to perform their research in an off-campus lab must submit a completed application to the BIOC 310 instructor at least 2 weeks prior to the start of classes and may not register for fewer than 3 credit hours. Instructor Permission Required. Recommended Prerequisite(s): Students are strongly advised to secure research advisors and register for the class well in advance of the start of classes. Repeatable for Credit.

Course URL: www.bioc.rice.edu/bioc310

BIOC 311 - ADVANCED EXPERIMENTAL BIOSCIENCES

Short Title: ADV EXPERIMENTAL BIOSCIENCES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hours: 2

Restrictions: Students with a class of Freshman may not enroll. Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 211 and BIOC 301 (may be taken concurrently)

Description: Advancement of biochemical laboratory methods, record keeping, technical communication skills, and research strategies. Students will maintain a research quality laboratory notebook and will submit a paper in the style of a journal article. Pre-req BIOC 301 may be taken concurrently with BIOC 311.

BIOC 313 - INTRODUCTORY SYNTHETIC BIOLOGY

Short Title: INTRODUCTORY SYNTHETIC BIO

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hours: 2

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOS 211 or BIOC 211

Description: Students learn molecular biological procedures commonly used to build and characterize synthetic genetic circuits. Teams of students work on a research project in the interdisciplinary field of synthetic biology. Students continue to develop technical communication skills.

Course URL: www.owlnet.rice.edu/~bios311/bios311/bios313/bios313.html

BIOC 318 - MICROBIOLOGY LABORATORY

Short Title: MICROBIOLOGY LABORATORY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hour: 1

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 211

Description: Team projects focusing on water analysis and isolation, culture, observation, assay, and identification of bacteria. Offered in the second half of each semester, self-scheduled after the first formal meetings.

Course URL: www.ruf.rice.edu/~bioslabs/bios318/

BIOC 320 - LABORATORY IN TISSUE CULTURE

Short Title: LABORATORY IN TISSUE CULTURE

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hour: 1

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOE 440 or STAT 440 or BIOC 311

Description: Introduction to tissue culture techniques, including cell passage, cell viability, and cell attachment and proliferation assays. Students complete quantitative analysis of their data. Engineering design and applications are featured in graded work. Sections 1 and 2 are taught during the first half of the semester. Sections 3 and 4 are taught during the second half of the semester. Students may be required to attend lab on a university holiday. Instructor Permission Required. Cross-list: BIOE 342.

BIOC 329 - ANIMAL BIOLOGY AND PHYSIOLOGY

Short Title: ANIMAL BIOLOGY AND PHYSIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 201 or EBIO 202

Description: The evolution and systematics of the animal kingdom with consideration of functional anatomy, comparative physiology, behavior, medical implications and resource management. Cross-list: EBIO 329. Mutually Exclusive: Credit cannot be earned for BIOC 329 and EBIO 529.

BIOC 331 - BIOLOGY OF INFECTIOUS DISEASES

Short Title: BIOLOGY OF INFECTIOUS DISEASES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): EBIO 213

Description: This course gives a broad overview of the biology of infectious diseases using examples from humans, plants, and animals. Topics include diversity of diseases, mechanisms of disease transmission, epidemiology, population regulation, evolution of virulence, disease dynamics in natural communities and disease invasion and conservation biology. Cross-list: EBIO 331.

BIOC 332 - SYSTEMS PHYSIOLOGY

Short Title: SYSTEMS PHYSIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 201 and (PHYS 101 and PHYS 102) or (PHYS 125 and PHYS 126)

Description: This course will teach the fundamentals of human physiology with a specific focus on the nervous, cardiovascular, respiratory, and urinary systems. Basic introductory engineering principles will be applied to the study of physiological systems. The course is aimed to be accessible to students with non-engineering backgrounds. Students may receive credit for only one of BIOE 302, BIOE 322, and BIOC 332. Cross-list: BIOE 302. Mutually Exclusive: Credit cannot be earned for BIOC 332 and BIOE 322.

BIOC 334 - EVOLUTION

Short Title: EVOLUTION

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): EBIO 202

Description: Principles of biological evolution. Topics include natural selection, adaptation, molecular evolution, formation of new species, the fossil record, biogeography, and principles of classification. Cross-list: EBIO 334.

Course URL: www.ruf.rice.edu/~queller/Bios334/

BIOC 335 - CELLULAR AND MOLECULAR ANIMAL PHYSIOLOGY

Short Title: CELL & MOL ANIMAL PHYSIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 201

Description: This course takes a functional approach to investigate animal physiology from a cellular and molecular perspective. Using an integrated and comparative approach, students learn how animals maintain homeostasis, including how they meet their energy needs, take up and transport oxygen, and maintain hydration and salt balance. Students will read primary literature to explore physiological adaptations for survival in extreme environments. Graduate/Undergraduate Equivalency: BIOC 536. Mutually Exclusive: Credit cannot be earned for BIOC 335 and BIOC 536.

BIOC 341 - CELL BIOLOGY

Short Title: CELL BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 201

Description: Molecular mechanisms of eukaryotic cell function. Structure, function, and biogenesis of all subcellular organelles. Cell-cell communication, cytoskeleton assembly and function, cell cycle control, and cell-cell adhesions. Emphasis will be on cytoplasmic events; molecular studies of transcription are taught in BIOC 302 and BIOC 344. RECOMMENDATION: BIOC 300 is recommended for students using advanced placement credit for BIOC 201 and students preferring additional foundational background prior to enrollment in BIOC 341.

BIOC 344 - MOLECULAR BIOLOGY AND GENETICS

Short Title: MOLECULAR BIOLOGY & GENETICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Description: Mendelian genetics, population genetics, mapping, gene expression and regulation, genetic engineering, DNA replication and recombination, human genetics, genetic disease and gene therapy. Recommended Prerequisite(s): BIOC 201.

BIOC 352 - PHYSICAL CHEMISTRY FOR THE BIOSCIENCES

Short Title: PHYS CHEM FOR BIOSCIENCES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): (PHYS 126 or PHYS 102 or PHYS 112 or PHYS 142) and BIOC 301

Description: Study of selected aspects of physical chemistry as it relates to the biosciences. Includes thermodynamics, reaction rate theory, quantum mechanics, and atomic and molecular structure.

BIOC 361 - METABOLIC ENGINEERING FOR GLOBAL HEALTH ENVIRONMENTS

Short Title: METAB ENG GLOBAL HEALTH ENVMNT

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): (BIOE 362 or GLHT 362) and (PHYS 126 or PHYS 102 or PHYS 112 or PHYS 142) and MATH 102

Description: Importance of nutritional and pharmaceutical compounds, impact of cost of compounds on global health; Overview of biochemical pathways; metabolite analysis; Genetic engineering and molecular biology tools for ME; Pharmaceuticals and drug discovery approaches (antibiotics, antivirals; anti-parasite compounds); anti-diarrhea treatments; vaccines. Cross-list: BIOE 361, GLHT 361.

Course URL: www.btb.rice.edu

BIOC 368 - CONCEIVING AND MISCONCEIVING THE MONSTROUS IN FICTION AND IN ART, IN MEDICINE AND IN BIOSCIENCE

Short Title: MONSTER

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Distribution Group: Distribution Group III

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Description: However various the forms of life, we draw boundaries between normal, not normal, and monstrous. From the Biosciences to the Arts, our conceptions of the "monstrous" illuminate our identity, perceptions, and fears. Priority for enrollment beyond the cap given to students also enrolled in ARTS 358. Cross-list: HUMA 368.

BIOC 371 - SEMINAR IN CONTEMPORARY BIOLOGICAL AND BIOMEDICAL RESEARCH

Short Title: BIOMEDICAL RESEARCH SEMINAR

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hour: 1

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 341 (may be taken concurrently) or BIOC 301 (may be taken concurrently)

Description: This course will offer students a close-up look at an area of contemporary biological and biomedical research in a small-group seminar setting. Each seminar will focus on a different area of research through reading and discussion of recent research articles in that focus area. The faculty discussion leader for each seminar will be drawn from Baylor College of Medicine, UT Health Science Center, MD Anderson Cancer Center, Rice and others. Please consult the course website for a complete listing of seminars offered each semester. Please refer to the following link for additional information: http://www.bioc.rice.edu/bioc371. Instructor Permission Required. Recommended Prerequisite(s): Students should check the courses website for additional prerequisites, notes from the instructor, and other information specific to each section. Repeatable for Credit.

Course URL: www.bioc.rice.edu/bioc371

BIOC 372 - IMMUNOLOGY

Short Title: IMMUNOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 201

Description: Cellular and molecular basis of innate and adaptive immune function in mammals. Graduate/Undergraduate Equivalency: BIOC 573. Recommended Prerequisite(s): BIOC 301 and BIOC 341. Mutually Exclusive: Credit cannot be earned for BIOC 372 and BIOC 573/BIOS 372.

BIOC 380 - FUNDAMENTAL NEUROSCIENCE SYSTEMS

Short Title: NEUROSYSTEMS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Description: This course will provide a broad overview of the brain's neural systems that subserve perception, learning, and behavior. The course will be highly integrative with thematic content including functional organization of the nervous system, neural encoding and decoding, sensory systems, motor systems, and high-level concept processing. Cross-list: NEUR 380, PSYC 380. Recommended Prerequisite(s): PSYC 101.

BIOC 385 - FUNDAMENTALS OF CELLULAR AND MOLECULAR NEUROSCIENCE

Short Title: FUNDAMENTALS OF NEUROSCIENCE

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Description: Cellular, molecular, and integrative mechanisms of neural function, including membrane and axon physiology, synaptic transmission and plasticity, sensory transduction and processing. Cross-list: NEUR 385. Graduate/Undergraduate Equivalency: BIOC 585. Recommended Prerequisite(s): BIOC 201. Mutually Exclusive: Credit cannot be earned for BIOC 385 and BIOC 585.

BIOC 390 - TRANSFER CREDIT IN BIOCHEMISTRY AND CELL BIOLOGY

Short Title: TRAN CREDIT BIOCHEM&CELL BIO

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Transfer

Credit Hours: 3

Course Level: Undergraduate Upper-Level

Description: For transfer of courses which have no current equivalent in the Rice curriculum, but which can be counted as 300 level BIOC lecture courses, in satisfying requirements for majors in Biosciences. Repeatable for Credit.

BIOC 393 - LABORATORY TRANSFER CREDIT IN BIOCHEMISTRY AND CELL BIOLOGY

Short Title: LAB TRANSFER CREDIT

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Transfer

Credit Hour: 1

Course Level: Undergraduate Upper-Level

Description: For transfer of an advanced laboratory course in the Biochemistry and Cell Biology that has no current equivalent in the Rice curriculum. Any student may receive a maximum of one credit of BIOC 393.

BIOC 401 - UNDERGRADUATE HONORS RESEARCH

Short Title: UNDERGRADUATE HONORS RESEARCH

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Research

Credit Hours: 5

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Description: The Biochemistry and Cell Biology Honors Research Program is a suite of courses offering our seniors and advanced juniors the opportunity to perform a two-semester, individual research project in a research laboratory in Biochemistry & Cell Biology. Students having performed BIOS/BIOC 310 research in an off-campus laboratory in the Texas Medical Center will also be eligible to apply to perform honors research in that laboratory. The Honors Research Program courses function as a set and must all be taken in the same academic year. Registration for any of the courses requires a commitment to register for all three. Requires at least 15 hours of laboratory research per week, a proposal (revised from application), monthly reports, and a formal progress report (abstract, aims, progress toward aims, discussion of results, plans for the spring semester). Prerequisites: strong performance in (BIOC 310, or HONS 470/471) and BIOC 211 and either BIOC 301 or BIOC 341. Research professor recommendation required. Application for admission required (BCB Honors Program OwlSpace Resources). Department Permission Required. Repeatable for Credit.

BIOC 402 - UNDERGRADUATE HONORS RESEARCH

Short Title: UNDERGRADUATE HONORS RESEARCH

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Research

Credit Hours: 5

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 401

Corequisite: BIOC 412

Description: The Biochemistry and Cell Biology Honors Research Program is a suite of courses offering our seniors and advanced juniors the opportunity to perform a two-semester, individual research project in a research laboratory in Biochemistry & Cell Biology. Students having performed BIOS/BIOC 310 research in an off-campus laboratory in the Texas Medical Center will also be eligible to apply to perform honors research in that laboratory. Registration for any of the courses requires a commitment to register for all three. Requires at least 15 hours of laboratory research per week, monthly reports, a thesis (substantial research paper) and a poster presentation at the Rice Undergraduate Research Symposium. Repeatable for Credit.

BIOC 412 - UNDERGRADUATE RESEARCH SEMINAR

Short Title: UNDERGRADUATE RESEARCH SEMINAR

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hour: 1

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 401

Corequisite: BIOC 402

Description: This companion seminar requires attendance at course meetings and a formal scientific presentation of research performed while enrolled in the Honors Research Program. Repeatable for Credit.

BIOC 413 - EXPERIMENTAL MOLECULAR BIOLOGY

Short Title: EXPERIMENTAL MOLECULAR BIO

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hour: 1

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 311

Description: Application of strategies in molecular biology to investigate gene expression and function with an emphasis on experimental design, data analysis, and data interpretation. Students will prepare a scientific poster. Offered second half of spring semester.

BIOC 415 - EXPERIMENTAL PHYSIOLOGY

Short Title: EXPERIMENTAL PHYSIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hour: 1

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 311

Description: Laboratory studies in membrane, nerve, and muscle physiology, with emphasis on experimental design, data analysis, and data interpretation.

Course URL: www.ruf.rice.edu/~bioslabs/bios415

BIOC 417 - EXPERIMENTAL CELL AND MOLECULAR NEUROSCIENCE

Short Title: ADV EXPERIMENTAL NEUROSCIENCE

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hour: 1

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): EBIO 202 and BIOC 212 and CAAM 210 and (STAT 305 or STAT 310 or STAT 312) and (BIOC 385 or NEUR 385)

Description: Students will explore the molecular properties of neurons and related cells using standard techniques in the field. Experiments will include manipulating exocytosis, examining protein expression levels in different brain regions of mice, and culturing primary neurons. Lessons will also include a brief lecture/discussion on fundamental principles within cellular and molecular neuroscience.

BIOC 424 - MICROBIOLOGY AND BIOTECHNOLOGY

Short Title: MICROBIOLOGY & BIOTECHNOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 201

Description: Structure and functions of microorganisms with emphasis on their environmental, industrial and medical importance. Graduate/Undergraduate Equivalency: BIOC 524. Recommended Prerequisite(s): BIOC 301 or Instructor Permission. Mutually Exclusive: Credit cannot be earned for BIOC 424 and BIOC 524.

BIOC 425 - PLANT MOLECULAR GENETICS AND DEVELOPMENT

Short Title: PLANT MOLECULAR GENETICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 301 or BIOC 341

Description: Novel aspects of plant biology and development with emphasis on molecular and genetic mechanisms. Plant responses to the environment and the use of bioengineering and other means to develop new plant products will also be covered. Graduate/Undergraduate Equivalency: BIOC 525. Mutually Exclusive: Credit cannot be earned for BIOC 425 and BIOC 525.

BIOC 442 - MOLECULES, MEMORY AND MODEL ANIMALS: METHODS IN BEHAVIORAL NEUROSCIENCE

Short Title: BEHAVIORAL NEUROSCIENCE

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): (BIOC 380 or NEUR 380 or PSYC 380 or BIOC 385 or NEUR 385) and (PSYC 203 or EBIO 321) and (STAT 305 or STAT 310 or STAT 312)

Description: This will be a combined lecture/discussion course on historical and current methods in behavioral neuroscience using primary literature. Topics will include the molecular basis of memory, genetic impacts on cognition, and possible epigenetic influences on behavior. Special emphasis will be placed on discussing different model organism and their benefits/drawbacks in neuroscience research.

BIOC 443 - ADVANCED CONCEPTS AND CRITICAL ANALYSIS IN MODERN DEVELOPMENTAL BIOLOGY

Short Title: DEVELOPMENT

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 341 or BIOC 301 or BIOC 344

Description: An advanced undergraduate and graduate level course, dedicated to analysis and evaluation of scientific inquiry into animal development. Textbook based lectures and discussions based on primary scientific literature are used to exemplify and evaluate concepts and methodology. Writing assignments, quizzes, midterm and final exam will be used to evaluate performance. Graduate/Undergraduate Equivalency: BIOC 544. Mutually Exclusive: Credit cannot be earned for BIOC 443 and BIOC 544.

BIOC 445 - ADVANCED MOLECULAR BIOLOGY AND GENETICS

Short Title: ADV MOLECULAR BIOL & GENETICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 301 or BIOC 344

Description: Molecular and genetic aspects of the regulation of gene expression as seen in simple prokaryotic systems and the model eukaryotic systems used for studies of development. Graduate/Undergraduate Equivalency: BIOC 545. Mutually Exclusive: Credit cannot be earned for BIOC 445 and BIOC 545.

BIOC 447 - EXPERIMENTAL BIOLOGY AND THE FUTURE OF MEDICINE

Short Title: BIOLOGY AND MEDICINE

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 301 or BIOC 341 or BIOC 344

Description: Current biological methods offer the potential to transform health care. We will examine the biology and methodology of emergent health care technologies such as stem cell therapy and personal genome sequencing to understand their potential to impact human health. Graduate/Undergraduate Equivalency: BIOC 547.

BIOC 449 - ADVANCED CELL AND MOLECULAR NEUROSCIENCE

Short Title: ADV CELL AND MOLECULAR NEURO

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): (BIOC 385 or NEUR 385) and BIOC 201 and BIOC 212 and MATH 102 and (STAT 305 or STAT 310 or STAT 312)

Description: This course will be an overview of advanced principles and techniques in cell and molecular neuroscience; subjects will include bio-electricity, cellular signaling, and the molecular mechanics of neuronal plasticity. The class will primarily be lecture driven. However, there will be seminar component – students will review primary scientific literature, discuss it in small groups, and present their findings. Recommended Prerequisite(s): NEUR 380 or BIOC 380 or PSYC 380.

BIOC 450 - VIRUSES AND INFECTIOUS DISEASES

Short Title: VIRUSES & INFECTIOUS DISEASES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 201 and BIOC 301 and BIOC 341

Description: Animal viruses, especially those relevant to human health, will be discussed. Topics primarily focus on virus structure and the molecular biology of the virus life cycle. Practical issues such as the history of viral diseases, clinical manifestations, laboratory diagnosis, management and prevention will also be discussed. Graduate/Undergraduate Equivalency: BIOC 550. Mutually Exclusive: Credit cannot be earned for BIOC 450 and BIOC 550.

BIOC 455 - COMPUTATIONAL SYNTHETIC BIOLOGY

Short Title: COMP SYNTHETIC BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): MATH 211

Description: Mathematical and computational techniques of cell biology and synthetic biology. Topics include deriving and implementing mathematical and computational models of cellular growth and division, evolution, gene regulation, synthetic gene circuits, enzymatic processing, and stochastic processes in biology. Graduate/Undergraduate Equivalency: BIOC 555. Recommended Prerequisite(s): CAAM 210

BIOC 460 - CANCER BIOLOGY

Short Title: CANCER BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 301 and BIOC 341

Description: Provides an integrated lecture series summarizing current knowledge in cancer biology and integrating current literature with basic concepts. Topics include: statistics of incidence/survival, types of cancer, pathology, the process of carcinogenesis and sources of carcinogens, genetic and epigenetic mechanisms and consequences, cancer progression, metastasis and current treatment options. Students will learn to use online databases to develop independent strategies for analyzing datasets. There will be several writing assignments and in class oral presentations of research articles. Graduate/Undergraduate Equivalency: BIOC 560. Mutually Exclusive: Credit cannot be earned for BIOC 460 and BIOC 560.

BIOC 464 - EXTRACELLULAR MATRIX

Short Title: EXTRACELLULAR MATRIX

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOS 341 or BIOC 341

Description: This course will address the biology, organization, mechanics, and turnover of extracellular matrix. There will be an emphasis on cells and cell-matrix interactions, matrix distribution within and design of connective tissues and organs techniques for quantitative analysis of matrix, techniques for measurement and modeling of connective tissue biomechanics, changes with growth and aging and tissue/matrix degradation. Cross-list: BIOE 464. Graduate/Undergraduate Equivalency: BIOC 523. Recommended Prerequisite(s): BIOE 372, BIOC 341. Mutually Exclusive: Credit cannot be earned for BIOC 464 and BIOC 523.

BIOC 470 - COMPUTATION WITH BIOLOGICAL DATA

Short Title: COMPUTATION WITH BIOL DATA

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): (BIOC 301 or BIOC 341 or BIOC 344) and MATH 102

Description: This course will teach programming and analysis techniques essential for modern research in the biological sciences. Students will learn the basics of programming in the MATLAB or Python scripting languages and applications to analyzing biological data. There will be a particular focus on quantitative image and sequence analysis. Graduate/Undergraduate Equivalency: BIOC 570. Mutually Exclusive: Credit cannot be earned for BIOC 470 and BIOC 570.

BIOC 481 - MOLECULAR BIOPHYSICS I

Short Title: MOLECULAR BIOPHYSICS I

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 301 or BIOC 352

Description: Focus on principles of common biophysical methods used for study of conformations and dynamics of biological macromolecules and assemblies. Topics cover spectroscopic methods (absorption, fluorescence, circular dichroism, epr, NMR), transport processes, sedimentation, calorimetry, mass spectrometry, crystallography, cryo-electron microscopy, atomic force microscopy, ligand-protein interactions, protein folding, single molecule detection, computer simulations, functional genomics and laboratory evolution. Biological examples will be used to demonstrate merits and complementarity in each of the biophysical methods. Graduate/Undergraduate Equivalency: BIOC 551.

BIOC 482 - STRUCTURAL BIOLOGY

Short Title: STRUCTURAL BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Graduate level students may not enroll.

Course Level: Undergraduate Upper-Level

Prerequisite(s): BIOC 301 and (PHYS 101 or PHYS 125) and (PHYS 102 or PHYS 126)

Description: Structural biology plays an important role in defining atomic structures of biomolecules and understanding relationships between structure, dynamics and function in living systems. This course will give an introduction to techniques of determining biomolecular structures, X-ray crystallography, NMR, and cryoelectron microscopy and discuss striking examples of the power of structural biology. Graduate/Undergraduate Equivalency: BIOC 552. Mutually Exclusive: Credit cannot be earned for BIOC 482 and BIOC 552.

BIOC 523 - EXTRACELLULAR MATRIX

Short Title: EXTRACELLULAR MATRIC

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: This course will address the biology, organization, mechanics, and turnover of extracellular matrix. There will be an emphasis on cells and cell-matrix interactions, matrix distribution within and design of connective tissues and organs techniques for quantitative analysis of matrix, techniques for measurement and modeling of connective tissue biomechanics, changes with growth and aging and tissue/matrix degradation. Additional projects will be required of graduate level students. Cross-list: BIOE 524. Graduate/Undergraduate Equivalency: BIOC 464. Recommended Prerequisite(s): BIOE 372, BIOC/BIOE 341. Mutually Exclusive: Credit cannot be earned for BIOC 523 and BIOC 464.

BIOC 524 - MICROBIOLOGY & BIOTECHNOLOGY

Short Title: MICROBIOLOGY & BIOTECHNOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Structure and functions of microorganisms with emphasis on their environmental, industrial and medical importance. Graduate/Undergraduate Equivalency: BIOC 424. Mutually Exclusive: Credit cannot be earned for BIOC 524 and BIOC 424.

BIOC 525 - PLANT MOLECULAR GENETICS AND DEVELOPMENT

Short Title: PLANT MOLECULAR GENETICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Novel aspects of plant biology and development with emphasis on molecular and genetic mechanisms. Plant responses to the environment and the use of bioengineering and other means to develop new plant products will also be covered Graduate/Undergraduate Equivalency: BIOC 425. Mutually Exclusive: Credit cannot be earned for BIOC 525 and BIOC 425.

BIOC 530 - LAB MODULE IN NMR SPECTROSCOPY AND MOLECULAR MODELING

Short Title: LAB MOD NMR SPECTROSCOPY&MOLEC

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hour: 1

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Prerequisite(s): BIOC 481 or BIOC 482 (may be taken concurrently) or BIOC 552 (may be taken concurrently) or BIOC 551

Description: The students will learn to set up, acquire, and process one-dimensional and basic two-dimensional NMR experiments. Spectral interpretation (3D molecular modeling of proteins and nucleic acids) for nucleic acids and proteins using homonuclear and heteronuclear data. Enrollment limited to 12, with priority to graduate students. Offered first half of the semester. BIOC 482/552 may be taken concurrently with BIOC 530.

BIOC 532 - LABORATORY MODULE IN OPTICAL SPECTROSCOPY AND KINETICS

Short Title: LAB MOD OPTICAL SPECTROSCOPY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 2

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Students learn the principles behind fluorescence, circular dichroism, analytical ultracentrifugation, spectroscopy and rapid kinetics by carrying out experiments with genetically engineered proteins and state-of-the-art equipment. Data will be interpreted and manipulated using curve-fitting and graphics software. Offered second half of the semester. Recommended Prerequisite(s): BIOC 352 or equivalent. Concurrent or previous enrollment in BIOC 481 or BIOC 551.

BIOC 533 - BIOINFORMATICS & COMPUTATIONAL BIOLOGY

Short Title: BIOINFORMATICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 2

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: An introduction to the emerging field of bioinformatics. A series of lectures, combined with hands-on exercises. The topics to be discussed include sequence comparison, structure analysis, phylogenetics, database searching, microarrays and proteomics. Recommended prerequisite(s): BIOC 301 or permission of instructor.

BIOC 535 - PRACTICAL X-RAY CRYSTALLOGRAPHY

Short Title: PRACT X-RAY CRYSTALLOGRAPHY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hours: 2

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Prerequisite(s): BIOC 552 (may be taken concurrently) or BIOC 482 (may be taken concurrently)

Description: This is an introduction to macromolecular crystallography with emphasis on crystallization methods, data acquisition, processing and molecular model-building. Approaches to solving structures will be discussed, as well as refinement of molecular models. Offered second half of the semester. Prerequisities are concurrent and may be taken the same semester.

BIOC 536 - CELLULAR AND MOLECULAR ANIMAL PHYSIOLOGY

Short Title: CELL & MOL ANIMAL PHYSIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: This course investigates animal physiology from a cellular and molecular perspective. Using an integrated and comparative approach, students learn how animals maintain homeostasis. Students will read primary literature to explore physiological adaptations for survival in extreme conditions. Graduate/Undergraduate Equivalency: BIOC 335. Mutually Exclusive: Credit cannot be earned for BIOC 536 and BIOC 335.

BIOC 537 - ADVANCED CRYSTALLOGRAPHY SEMINAR

Short Title: ADV CRYSTALLOGRAPHY SEMINAR

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hour: 1

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: One hour seminar course in theoretical and practical aspects of crystallography, primarily as it applies to macromolecular crystallography. Presentations will be given by instructors and students on advanced topics based on published works or original research. Repeatable for Credit.

BIOC 540 - METABOLIC ENGINEERING

Short Title: METABOLIC ENGINEERING

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Principles of metabolic engineering: overview of biochemical pathways; kinetics and thermodynamics of metabolic networks; genetic engineering and molecular biology tools; metabolic flux analysis using stoichiometric and labeling techniques; metabolic control analysis. Metabolic engineering in the postgenomic era; functional genomics and systems biology. Emerging applications: chemicals from biorenewables; food ingredients; health and disease. Cross-list: CHBE 640.

BIOC 544 - ADVANCED CONCEPTS AND CRITICAL ANALYSIS IN MODERN DEVELOPMENTAL BIOLOGY

Short Title: DEVELOPMENT

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Prerequisite(s): BIOC 341 or BIOC 301 or BIOC 344

Description: An advanced undergraduate and graduate level course, dedicated to analysis and evaluation of scientific inquiry into animal development. Textbook based lectures and discussions based on primary scientific literature are used to exemplify and evaluate concepts and methodology. Writing assignments, quizzes, midterm and final exam will be used to evaluate performance. Graduate/Undergraduate Equivalency: BIOC 443. Mutually Exclusive: Credit cannot be earned for BIOC 544 and BIOC 443.

BIOC 545 - ADVANCED MOLECULAR BIOLOGY AND GENETICS

Short Title: ADV MOLECULAR BIOL & GENETICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Molecular and genetic aspects of the regulation of gene expression as seen in simple prokaryotic systems and the model eukaryotic systems used for studies of development. Graduate/Undergraduate Equivalency: BIOC 445. Mutually Exclusive: Credit cannot be earned for BIOC 545 and BIOC 445.

BIOC 547 - EXPERIMENTAL BIOLOGY AND THE FUTURE OF MEDICINE

Short Title: BIOLOGY AND MEDICINE

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Current biological methods offer the potential to transform health care. We will examine the biology and methodology of emergent health care technologies such as stem cell therapy and personal genome sequencing to understand their potential to impact human health. Graduate/Undergraduate Equivalency: BIOC 447. Recommended Prerequisite(s): BIOC 301 or BIOC 341 or BIOC 344.

BIOC 550 - VIRUSES AND INFECTIOUS DISEASES

Short Title: VIRUSES & INFECTIOUS DISEASES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Prerequisite(s): BIOC 201 and BIOC 301 and BIOC 341

Description: Animal viruses, especially those relevant to human health, will be discussed. Topics primarily focus on virus structure and the molecular biology of the virus life cycle. Practical issues such as the history of viral diseases, clinical manifestations, laboratory diagnosis, management and prevention will also be discussed. Graduate/Undergraduate Equivalency: BIOC 450. Mutually Exclusive: Credit cannot be earned for BIOC 550 and BIOC 450.

BIOC 551 - MOLECULAR BIOPHYSICS

Short Title: MOLECULAR BIOPHYSICS I

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Prerequisite(s): BIOC 301 or BIOC 352

Description: Focus on principles of common biophysical methods used for study of conformations and dynamics of biological macromolecules and assemblies. Topics cover spectroscopic methods (absorption, fluorescence, circular dichroism, epr, NMR), transport processes, sedimentation, calorimetry, mass spectrometry, crystallography, cryo-electron microscopy, atomic force microscopy, ligand-protein interactions, protein folding, single molecule detection, computer simulations, functional genomics and laboratory evolution. Biological examples will be used to demonstrate merits and complementarity in each of the biophysical methods. Graduate/Undergraduate Equivalency: BIOC 481.

BIOC 552 - STRUCTURAL BIOLOGY

Short Title: STRUCTURAL BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Prerequisite(s): (PHYS 101 or PHYS 125) and (PHYS 102 or PHYS 126)

Description: Structural biology plays an important role in defining atomic structures of biomolecules and understanding relationships between structure, dynamics and function in living systems. This course will give an introduction to techniques of determining biomolecular structures, X-ray crystallography, NMR, and cryoelectron microscopy and discuss striking examples of the power of structural biology. Graduate/Undergraduate Equivalency: BIOC 482. Recommended prerequisite(s): BIOC 301. Mutually Exclusive: Credit cannot be earned for BIOC 552 and BIOC 482.

BIOC 555 - COMPUTATIONAL SYNTHETIC BIOLOGY

Short Title: COMP SYNTH BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Mathematical and computational techniques of cell biology and synthetic biology. Topics include deriving and implementing mathematical and computational models of cellular growth and division, evolution, gene regulation, synthetic gene circuits, enzymatic processing, and stochastic processes in biology. Graduate/Undergraduate Equivalency: BIOC 455.

BIOC 558 - ADVANCES IN NUCLEASE-MEDIATED GENOME ENGINEERING

Short Title: ADV NUCLEASE-MEDIATED GEN ENG

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: This course provides a comprehensive understanding of advances in the nuclease-mediated genome engineering field. Past and current stages of genome-editing technologies, the fundamental mechanisms of different classes of genome-editing nucleases, and cutting-edge strategies for engineering novel genome-editing agents and their applications in synthetic biology and therapeutics. Cross-list: CHBE 558.

BIOC 560 - CANCER BIOLOGY

Short Title: CANCER BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Provides an integrated lecture series summarizing current knowledge in cancer biology and integrating current literature with basic concepts. Topics include: statistics of incidence/survival, types of cancer, pathology, the process of carcinogenesis and sources of carcinogens, genetic and epigenetic mechanisms and consequences, cancer progression, metastasis and current treatment options. Students will learn to use online databases to develop independent strategies for analyzing datasets. There will be several writing assignments and in class oral presentations of research articles. This course requires instructor permission to enroll. Please fill out the special registration form from https://registrar.rice.edu/student/special_registration. All requests will be reviewed and you will be notified of an enrollment decision. Instructor Permission Required. Cross-list: BIOE 560. Graduate/Undergraduate Equivalency: BIOC 460. Mutually Exclusive: Credit cannot be earned for BIOC 560 and BIOC 460.

BIOC 570 - COMPUTATION WITH BIOLOGICAL DATA

Short Title: COMPUTATION WITH BIOL DATA

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: This course will teach programming and analysis techniques essential for modern research in the biological sciences. Students will learn the basics of programming in the MATLAB or Python scripting languages and applications to analyzing biological data. There will be a particular focus on quantitative image and sequence analysis. Instructor Permission Required. Graduate/Undergraduate Equivalency: BIOC 470. Mutually Exclusive: Credit cannot be earned for BIOC 570 and BIOC 470.

BIOC 571 - BIOINFORMATICS: SEQUENCE ANALYSIS

Short Title: BIOINFORMATICS: SEQUENCE

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Pairwise and multiple sequence alignment, Markov chains and HMMs, Phylogenetic reconstruction, Haplotype inference, Computational models of RNA structure, Gene finding, Genome rearrangements, and comparative genomics. Cross-list: COMP 571.

Course URL: www.cs.rice.edu/~nakhleh/COMP571/

BIOC 572 - BIOINFORMATICS: NETWORK ANALYSIS

Short Title: BIOINFORMATICS: NETWORKS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: This course covers computational aspects of biological network analysis, a major theme in the area of systems biology. The course addresses protein-protein interaction networks, signaling, and metabolic networks, and covers issues related to reconstructing, analyzing, and integrating various types of networks. Cross-list: BIOE 564, COMP 572.

Course URL: www.cs.rice.edu/~nakhleh/COMP572/

BIOC 573 - IMMUNOLOGY

Short Title: IMMUNOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Prerequisite(s): BIOC 201

Description: Cellular and molecular basis of innate and adaptive immune function in mammals. Graduate students will be required to do all the usual assignments associated with the undergraduate section of the course but in addition will write a substantial paper on some aspects of the field that is relevant to their planned careers in biomedical research/biotechnology. Graduate/Undergraduate Equivalency: BIOC 372. Recommended Prerequisite(s): BIOC 301 AND BIOC 341. Mutually Exclusive: Credit cannot be earned for BIOC 573 and BIOC 372.

BIOC 575 - INTRODUCTION TO RESEARCH

Short Title: INTRODUCTION TO RESEARCH

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hour: 1

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Introduction of first-year graduate students to the research programs and laboratories of individual faculty members. Open only to BCB graduate students.

BIOC 576 - FOUNDATIONS OF BIOTECHNOLOGY

Short Title: FOUNDATIONS OF BIOTECHNOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hour: 1

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Graduate level introduction to a wide range of research methods in biosciences and bioengineering. Individual faculty members from the Biosciences and Bioengineering will each present practices and techniques for their areas of expertise. A web-based methods database will be constructed, with student involvement, from the library of lectures. Cross-list: BIOE 576.

BIOC 577 - FOUNDATIONS OF BIOTECHNOLOGY

Short Title: FOUNDATIONS OF BIOTECHNOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hour: 1

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Graduate level introduction to a wide range of research methods in biosciences and bioengineering. Individual faculty members from the biosciences and bioengineering will each present practices and techniques for their areas of expertise. A web-based methods database will be constructed, with student involvement, from the library of lectures. Cross-list: BIOE 577.

BIOC 578 - BIOTECHNOLOGY PRACTICUM

Short Title: BIOTECHNOLOGY PRACTICUM

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Internship/Practicum

Credit Hour: 1

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: This course is part of the NIH Biotechnology Training Program and is limited to program participants. Students will receive exposure and training in cutting edge concepts and technologies. Cross-list: BIOE 578.

BIOC 580 - PROTEIN ENGINEERING

Short Title: PROTEIN ENGINEERING

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Manipulation of gene expression in prokaryotic and eukaryotic cells. Rational design and directed solutions for cell and protein engineering. Selection and screening technologies and process optimization. Synthetic Biology: engineering and application of gene circuits. Molecular biotechnology applications: Diagnosis, Therapeutics and Vaccines. Cross-list: BIOE 580, CHBE 580. Recommended Prerequisite(s): CHBE 310/510 or equivalent is highly recommended.

BIOC 581 - GRADUATE SEMINAR IN BIOCHEMISTRY AND CELL BIOLOGY

Short Title: GRAD SEM BIOCHEM & CELL BIOL

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hour: 1

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: A discussion of selected research topics. Required of all Biochemistry and Cell Biology graduate students. Open only to BCB graduate students. Repeatable for Credit.

BIOC 582 - GRADUATE SEMINAR IN BIOCHEMISTRY AND CELL BIOLOGY

Short Title: GRAD SEM/BIOCHEM & CELL BIOL

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hour: 1

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: A discussion of selected research topics. Required of all Biochemistry and Cell Biology graduate students. Open only to BCB graduate students. Repeatable for Credit.

BIOC 583 - MOLECULAR INTERACTIONS

Short Title: MOLECULAR INTERACTIONS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 4

Restrictions: Enrollment is limited to students with a major in Biochemistry and Cell Biology. Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: First of two integrated classes taken by first-year graduate students in BCB (to be followed by BIOC 588, Cellular Interactions). Covers advanced topics in biochemistry, ranging from protein and nucleic acid synthesis, folding, function, and engineering to allostery, dynamics, and degradation with an emphasis on fundamental principles, research methodologies, problem solving, and critical analysis of primary literature. Enrollment limited to BCB graduate students.

BIOC 585 - FUNDAMENTALS OF CELLULAR AND MOLECULAR NEUROSCIENCE

Short Title: FUNDAMENTALS OF NEUROSCIENCE

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Cellular, molecular, and integrative mechanisms of neural function, including membrane and axon physiology, synaptic transmission and plasticity, sensory transduction and processing. Graduate/Undergraduate Equivalency: BIOC 385. Recommended Prerequisite(s): BIOC 201. Mutually Exclusive: Credit cannot be earned for BIOC 585 and BIOC 385.

BIOC 587 - RESEARCH DESIGN, PROPOSAL WRITING, AND PROFESSIONAL DEVELOPMENT

Short Title: PROPOSAL WRITING

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Preparation for professional scientific communication with an emphasis on writing research proposals, describing work in progress, and presenting data in context of research goals.

BIOC 588 - CELLULAR INTERACTIONS

Short Title: CELLULAR INTERACTIONS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 4

Restrictions: Enrollment is limited to students with a major in Biochemistry and Cell Biology. Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Second of two integrated classes taken by first-year graduate students in BCB (following BIOC 583, Molecular Interactions). Covers advanced topics in genetics, cell biology, and developmental biology, focusing on cellular, tissue, and organismal structure and function with an emphasis on fundamental principles, research methodologies, and critical analysis of primary literature.

BIOC 589 - COMPUTATIONAL MOLECULAR BIOENGINEERING/BIOPHYSICS

Short Title: COMP MOLECULAR BIOENG/BIOPHYS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: This is a course designed for students in computationally-oriented biomedical and bioengineering majors to introduce the principles and methods used for the simulations and modeling of macromolecules of biological interest. Protein conformation and dynamics are emphasized. Empirical energy function and molecular dynamics calculations, as well as other approaches, are described. Specific biological problems are discussed to illustrate the methodology. Cross-list: BIOE 589. Recommended Prerequisite(s): MATH 212, BIOC 301, BIOE 332.

BIOC 590 - SPECIAL TOPICS IN BIOCHEMISTRY AND CELL BIOLOGY

Short Title: SPEC TOPCS BIOCHEM&CELL BIO

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hour: 1

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Development of specific topic areas at the graduate level. Instructor Permission Required.

BIOC 592 - TOPICS IN QUANTITATIVE BIOLOGY AND BIOMEDICAL INFORMATICS (KECK SEMINAR)

Short Title: TOPICS QUANT BIO & BIOMED INFO

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hour: 1

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: A discussion of selected research topics in quantitative biology and biomedical informatics. Cross-list: KECK 592. Repeatable for Credit.

BIOC 593 - CURRENT TOPICS IN PLANT BIOLOGY

Short Title: TOPICS IN PLANT BIOLOGY

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hour: 1

Restrictions: Enrollment is limited to students with a major in Biochemistry and Cell Biology. Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Discussion of selected research topics in current plant biology literature. Repeatable for Credit.

BIOC 599 - GRADUATE TEACHING IN BIOCHEMISTRY AND CELL BIOLOGY

Short Title: GRADUATE TEACHING IN BIOCHEM

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Independent Study

Credit Hour: 1

Restrictions: Enrollment is limited to students with a major in Biochemistry and Cell Biology. Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Supervised instruction in teaching biochemistry and cell biology. Repeatable for Credit.

BIOC 611 - RESEARCH SEMINAR IN BIOCHEMISTRY AND CELL BIOLOGY

Short Title: RESEARCH SEMINAR

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hour: 1

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Discussion of individual research or current topics in particular areas. Intended for students conducting research projects in the lab of the instructor. Repeatable for Credit.

BIOC 643 - CELL MECHANICS, MECHANOTRANSDUCTION AND THE CELL MICROENVIRONMENT

Short Title: MECHANOTRANSDUCTION

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Mechanotransduction is a fundamental process essential for living systems and plays a fundamental role in cell signaling, cancer metastasis and stem cell differentiation. Additionally, fundamental biological processes such as endocytosis cell fusion and cell migration are driven by a coordinated interplay of molecular interactions that drive membrane deformation. This course will survey the current understanding of mechanotransduction and the mechanical properties of cells and their microenvironment, including membrane and cytoskeletal mechanics. Experimental approaches for measuring and manipulating the material properties of cells and their environment; including optical, electrical and magnetic techniques will be covered. A variety of application will be covered, including manipulation in engineering of mechanotransduction pathways to drive cell migration and stem cell differentiation. Instructor Permission Required. Cross-list: BIOE 643, PHYS 643.

BIOC 701 - GRADUATE LAB RESEARCH I

Short Title: GRADUATE LAB RESEARCH I

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Research

Credit Hours: 2-4

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Graduate research in Biochemistry and Cell Biology. Designed for short term laboratory projects for first year graduate students. Recommended prerequisite(s): Graduate standing in Biochemistry and Cell Biology. Repeatable for Credit.

BIOC 702 - GRADUATE LAB RESEARCH II

Short Title: GRADUATE LAB RESEARCH II

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Research

Credit Hours: 2-4

Restrictions: Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Graduate research in Biochemistry and Cell Biology. Designed for short term laboratory projects for first year graduate students. Recommended prerequisite(s): Graduate standing in Biochemistry and Cell Biology. Repeatable for Credit.

BIOC 800 - BIOCHEMISTRY & CELL BIOLOGY GRADUATE RESEARCH

Short Title: BCB GRADUATE RESEARCH

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Research

Credit Hours: 1-15

Restrictions: Enrollment is limited to students with a major in Biochemistry and Cell Biology. Enrollment is limited to Graduate level students.

Course Level: Graduate

Description: Repeatable for Credit.